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Ketoconazole (Nizoral)

Ketoconazole is an antifungal drug available in tablets, as a cream, and as a shampoo. Manufactured by Janssen Pharmaceuticals, it is

used to fight yeast infections, oral thrush, ringvvorm, and hard totreat fungal skin infections. Ketoconazole may also be helpful in treating androgenetic alopecia.


Ketoconazole appears to interfere with the production of testosterone and acts as an anti inflammatory agenttwo reasons why it has been investigated for the treatment of androgenetic alopecia.

A 1998 study conducted at the University of Liege in Belgium found that ketoconazole shampoo used alone or in combination vvith minoxidil increased the size and density of hair, as well as shifted more hair follicles into their grovvth cycle. Investigators speculate that ketoconazole may reduce levels of testosterone around the hair follicles. Ketoconazole is a nonsteroidal agent.

Even though the findings of this study are good news, more research is needed to verify the results. Further, no tests have yet been conducted on ketoconazole tablets and their effect on baldness.


According to the Physicians’ Desk Ref erence, side effects from using ketoconazole shampoo are extremely rare. A tiny percentage of people may experience itching, mild dryness of the skin, abnormal hair texture, and scalp irritation.

Potential side effects of taking ketoconazole tablets include abdominal pain, itching, nausea, and vomiting. Ketoconazole can interact dangerously vvith numerous other drugs. || you’re taking other medications, be sure to let your physician and pharmacist knovv before combining ketoconazole vvith other drugs.

NOTE: According to the Physicians’ Desk Ref erence, before considering ketoconazole check vvith your doctor if:

• You are allergic to the drug.
• You are pregnant, plan to become pregnant, or are nursing.
• You are taking other prescription or nonprescription drugs.

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