HOW DOES İT WORK?
No one really knows for certain how minoxidil works to promote hair growth. Even so, there are some theories, based on scientific research. First, minoxidil is a vasodilator, meaning that it opens up blood vessels in the scalp. Blood can thus circulate more freely to the scalp and deliver more oxygen and nutrients to the hair follicles. The net effect may be to jolt hair follicles from their resting phase into their grovvth phase.
Second, minoxidil enlarges withered (miniaturized) hair follicles. Miniaturization occurs when androgens and other factors gradually shrink the hair follicles, choking off hair grovvth. By enlarging the hair follicle, minoxidil extends the life of the hairgrovving cycle and gets hair grovving again.
And third, minoxidil appears to promote celi division in keratinocytes, particularly those located in and around the hair follicle. Keratinocytes are cells that produce the hair protein keratin.
MINOXIDIL AND ANDROGENETİC ALOPECİA
Currently, minoxidil is the only medically approved treatment for women with androgenetic alopecia (hereditary hair loss). It appears to work very effectively for women. Here’s a look at some of the research:
Regrows hain The earliest studies on minoxidil were conducted in 1982 and 1983 by Upjohn, the makers of Rogaine. In clinical trials at twenty seven medical centers across the country, a 2 percent solution of topical minoxidil or a placebo was given to 2,300 participants (mostly men and a few women), aged eighteen to forty nine. The studies lasted four months, and by the end of the research period, 39 percent of the minoxidil group were showing new hair growthsome of it quite dense.
Studies with mostly vvomen were conducted later. In 1993, Upjohn tested 2 percent minoxidil in a study of 294 vvomen in ten centers throughout Europe. Ali suffering from androgenetic alopecia, the vvomen were divided into a minoxidil group and a placebo group. The study lasted thirty two vveeks. Forty four percent of those vvomen in the 2 percent minoxidil group achieved new hair grovvth, compared to 29 percent in the placebo group.
A similar study vvas conducted in 1994 at the University of Texas in San Antonio. In eleven centers throughout the United States, 256 vvomen (ages eighteen to forty five) vvith androgenetic alopecia applied 2 percent minoxidil or a placebo to their scalps tvvice daily for thirty tvvo vveeks. Approximately 63 percent of the minoxidil treated vvomen showed minimal to moderate regrovvth. Those in the placebo group did not fare as vvell. Increases scalp coverage. Topical minoxidil increases the number of hairs on your head, according to several well designed studies.